TIME-DELAY FEEDBACK CONTROL OF COMPLEX PATHOLOGICAL RHYTHMS IN AN ATRIOVENTRICULAR CONDUCTION MODEL

We describe the emergence of complex cardiac rhythms in a nonlinear model of the atrioventricular (AV) nodal conduction system, and a method based on linear time-delay feedback (LTDF) control for suppressing them. The LTDF controller is effective at suppressing these rhythms by stabilizing the map to one of a set of unstable fixed points. Additionally, we show that the method is robust to both measurement error and experimental noise.