Tie2-dependent knockout of HIF-1 impairs burn wound vascularization and homing of bone marrow-derived angiogenic cells

Kakali Sarkar; Sergio Rey; Xianjie Zhang; Raul Sebastian; Guy P. Marti; Karen Fox-Talbot; Amanda V. Cardona; Junkai Du; Yee Sun Tan; Lixin Liu; Frank Lay; Frank J. Gonzalez; John W. Harmon; Gregg L. Friedman

doi:10.1093/cvr/cvr282

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Tie2-dependent knockout of HIF-1 impairs burn wound vascularization and homing of bone marrow-derived angiogenic cells

Article 2011 en

Abstract

1 min read

HIF-1 activity in Tie2-lineage cells is required for the mobilization and homing of BMDACs to cutaneous burn wounds and for the vascularization of burn wound tissue.

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