Therapy-Induced Tumor Immunosurveillance Involves IFN-Producing Killer Dendritic Cells

Evelyn Ullrich; Mathieu Bonmort; Grégoire Mignot; Nathalie Chaput; Julien Taı̈eb; Cédric Menard; Sophie Viaud; Thomas Tursz; Guido Guido Kroemer; Laurence Zitvogel

doi:10.1158/0008-5472.can-06-3766

Abstract

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Abstract A unique class of IFN-producing killer dendritic cells (IKDC) resembling natural killer cells has been defined that can recognize and lyse tumor cells through a tumor necrosis factor–related apoptosis-inducing ligand–dependent mechanism. IKDC may mediate the host-dependent antitumor activity of Gleevec/STI571 and other therapeutics that can inhibit the c-kit tyrosine kinase. IKDC represent an important new component of the innate immune system responding to cancer. [Cancer Res 2007;67(3):851–3]

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Data from The Dendritic Cell–like Functions of IFN-Producing Killer Dendritic Cells Reside in the CD11b+ Subset and Are Licensed by Tumor Cells

Preprint2023

Data from The Dendritic Cell–like Functions of IFN-Producing Killer Dendritic Cells Reside in the CD11b+ Subset and Are Licensed by Tumor Cells

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Supplementary Figure 1 from The Dendritic Cell–like Functions of IFN-Producing Killer Dendritic Cells Reside in the CD11b+ Subset and Are Licensed by Tumor Cells

Therapy-Induced Tumor Immunosurveillance Involves IFN-Producing Killer Dendritic Cells

Abstract

Discussion(0)

Related publications

A novel dendritic cell subset supporting the concept of tumor immunoediting: IFN producing Killer Dendritic cell (IKDC)

The Dendritic Cell–like Functions of IFN-Producing Killer Dendritic Cells Reside in the CD11b+ Subset and Are Licensed by Tumor Cells

Data from The Dendritic Cell–like Functions of IFN-Producing Killer Dendritic Cells Reside in the CD11b<sup>+</sup> Subset and Are Licensed by Tumor Cells

Data from The Dendritic Cell–like Functions of IFN-Producing Killer Dendritic Cells Reside in the CD11b<sup>+</sup> Subset and Are Licensed by Tumor Cells

Supplementary Figure 1 from The Dendritic Cell–like Functions of IFN-Producing Killer Dendritic Cells Reside in the CD11b<sup>+</sup> Subset and Are Licensed by Tumor Cells

Therapy-Induced Tumor Immunosurveillance Involves IFN-Producing Killer Dendritic Cells

Abstract

Discussion(0)

Related publications

A novel dendritic cell subset supporting the concept of tumor immunoediting: IFN producing Killer Dendritic cell (IKDC)

The Dendritic Cell–like Functions of IFN-Producing Killer Dendritic Cells Reside in the CD11b+ Subset and Are Licensed by Tumor Cells

Data from The Dendritic Cell–like Functions of IFN-Producing Killer Dendritic Cells Reside in the CD11b&lt;sup&gt;+&lt;/sup&gt; Subset and Are Licensed by Tumor Cells

Data from The Dendritic Cell–like Functions of IFN-Producing Killer Dendritic Cells Reside in the CD11b&lt;sup&gt;+&lt;/sup&gt; Subset and Are Licensed by Tumor Cells

Supplementary Figure 1 from The Dendritic Cell–like Functions of IFN-Producing Killer Dendritic Cells Reside in the CD11b&lt;sup&gt;+&lt;/sup&gt; Subset and Are Licensed by Tumor Cells

Data from The Dendritic Cell–like Functions of IFN-Producing Killer Dendritic Cells Reside in the CD11b<sup>+</sup> Subset and Are Licensed by Tumor Cells

Data from The Dendritic Cell–like Functions of IFN-Producing Killer Dendritic Cells Reside in the CD11b<sup>+</sup> Subset and Are Licensed by Tumor Cells

Supplementary Figure 1 from The Dendritic Cell–like Functions of IFN-Producing Killer Dendritic Cells Reside in the CD11b<sup>+</sup> Subset and Are Licensed by Tumor Cells