Currently the most frequently pursued drugs for the treatment of herpesvirus infections are acyclovir, ganciclovir, and foscarnet. However, clinical usefulness of these compounds is limited by toxicity (particularly in ganciclovir and foscarnet use) and by the emergence of drug-resistant viruses in immunosuppressed patients. Therefore, the development of new, effective antiherpesvirus drugs is one of the top priorities in current antiviral drug research.
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