The observation of a better outcome associated with decreasing blood lactate concentrations was consistent throughout the clinical studies, and was not limited to septic patients. In all groups, the changes are relatively slow, so that lactate measurements every 1-2 hrs are probably sufficient in most acute conditions. The value of lactate kinetics appears to be valid regardless of the initial value.
Ludhmila Abrahão Hajjar, Jean Louis Vincent, F Galas, Jáder Pereira Almeida, Fábio Biscegli Jatene, P Bueno, J Fukushima, Rosana Ely Nakamura, C. M. Silva, Roberto Kalil Filho, José Otávio Costa Auler Júnior
Ludhmila Abrahão Hajjar, Rosana Ely Nakamura, Juliano Pinheiro de Almeida, Júlia Tizue Fukushima, Paulo M. Hoff, Jean Louis Vincent, José Otávio Costa Auler Júnior
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