The Timing of Early Antibiotics and Hospital Mortality in Sepsis

Jean Louis Vincent; Vikram Fielding‐Singh; J Greene; Jennifer M. Baker; Theodore J. Iwashyna; Jay Bhattacharya; Gabriel J. Escobar

doi:10.1164/rccm.201609-1848oc

Abstract

1 min read

In a large, contemporary, and multicenter sample of patients with sepsis in the emergency department, hourly delays in antibiotic administration were associated with increased odds of hospital mortality even among patients who received antibiotics within 6 hours. The odds increased within each sepsis severity strata, and the increased odds of mortality were greatest in septic shock.

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