The synthesis of cyanoformamides via a CsF-promoted decyanation/oxidation cascade of 2-dialkylamino-malononitriles

Lin-sheng Lei; Cao-Gen Xue; Xue-Tao Xu; Da‐Ping Jin; Shao‐Hua Wang; Wen Bao; Huan Liang; Kun Zhang; Abdullah Mohamed Asiri

doi:10.1039/c9ob00510b

Abstract

1 min read

A mild and efficient method for the synthesis of cyanoformamides from N,N-disubstituted aminomalononitriles with CsF as the promoter has been developed. This method features a wide substrate scope and high reaction efficiency, and will facilitate corresponding cyanoformamide-based biological studies and synthetic methodology development.

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The synthesis of cyanoformamides <i>via</i> a CsF-promoted decyanation/oxidation cascade of 2-dialkylamino-malononitriles

Abstract

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