Systematic reviewers should identify existing reviews as a compulsory first step
Systematic reviews occupy a central position in evidence based medicine. They are the starting point of a well developed practice guideline. Some funders of randomised trials ask investigators for a strong rationale for their proposed trial, indicating that the best evidence is likely to be a well conducted and completely reported systematic review.1 These reasons, and others, probably explain the popularity and publication trajectory of systematic reviews.2 Does this translate into duplication of effort and waste? In a linked paper (doi:10.1136/bmj.f4501), using sound methodology and complete and transparent reporting, Siontis and colleagues examined this question.3
Having selected 73 meta-analyses published during 2010, the authors identified two thirds of them as having at least one overlapping meta-analysis. The good news is that duplication does not seem to have been a major problem. The authors report a median of two overlapping meta-analyses per topic. However, for several clinical topics there were multiple duplicates, and in 17 instances at least one author was involved in more than one overlapping meta-analysis. These findings provide another …
Jelena Savović, Ross Harris, Lesley Wood, Rebecca Beynon, Doug Altman, Bodil Als‐Nielsen, Ethan M. Balk, Jonathan J Deeks, Lise Lotte Gluud, Christian Gluud, John P A Ioannidis, Peter Jüni, David Moher, Julie Pildal, Kenneth F. Schulz, Jonathan A C Sterne
Brian Hutton, Georgia Salanti, Deborah M Caldwell, Anna Chaimani, Christopher H. Schmid, Chris Cameron, John P A Ioannidis, Sharon E. Straus, Kristian Thorlund, Jeroen P. Jansen, Cynthia D. Mulrow, Ferrán Catalá-López, Peter C Gøtzsche, Kay Dickersin, Isabelle Boutron, Douglas G. Altman, David Moher
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