The megalin/gp330 receptor is involved in the capability of hepatic stellate cells to bind and internalize vitamin D binding protein (Gc-globulin) — OA Gressner (2008) | RDL Network
The megalin/gp330 receptor is involved in the capability of hepatic stellate cells to bind and internalize vitamin D binding protein (Gc-globulin)
Article 2008 en
Authors
OG
OA Gressner
BL
Birgit Lahme
AG
AM Gressner
Abstract
1 min read
Aims: Vitamin D binding protein (DBP) is a highly expressed, multifunctional and polymorphic serum protein, which also serves as the major transporter for vitamin D sterols. The present study was performed to analyze the pathophysiological interaction between DBP and hepatocytes (PC) or hepatic stellate cells (HSC), the most important fat-/retinol- storing cells in the liver that spontaneously transdifferentiate to myofibroblasts (MFB) in culture.
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