THE IMMUNOSUPPRESSIVE AGENT MYCOPHENOLATE MOFETIL MARKEDLY POTENTIATES THE ACTIVITY OF LOBUCAVIR [1R(1??,2??,3??)]-9-[2,3-BIS(HYDROXYMETHYL)-CYCLOBUTYL]GUANINE AGAINST DIFFERENT HERPES VIRUSES1

Johan Neyts; De Clercq Erik

doi:10.1097/00007890-199903150-00022

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De Clercq Erik

KU Leuven

THE IMMUNOSUPPRESSIVE AGENT MYCOPHENOLATE MOFETIL MARKEDLY POTENTIATES THE ACTIVITY OF LOBUCAVIR [1R(1??,2??,3??)]-9-[2,3-BIS(HYDROXYMETHYL)-CYCLOBUTYL]GUANINE AGAINST DIFFERENT HERPES VIRUSES1

Article 1999 en

Authors

JN
Johan Neyts
De Clercq Erik
KU Leuven

Abstract

1 min read

MMF markedly potentiates the activity of LBV against HSV-1, HSV-2, TK- HSV-1, and CMV. This drug interaction may have important implications when using LBV in the treatment of intercurrent herpesvirus infections in transplant recipients under MMF therapy.

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THE IMMUNOSUPPRESSIVE AGENT MYCOPHENOLATE MOFETIL MARKEDLY POTENTIATES THE ACTIVITY OF LOBUCAVIR [1R(1??,2??,3??)]-9-[2,3-BIS(HYDROXYMETHYL)-CYCLOBUTYL]GUANINE AGAINST DIFFERENT HERPES VIRUSES1

Abstract

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