From the Laboratory of Gene Regulation and Signal Transduction, the Department of Pharmacology, University of California, San Diego, La Jolla, CA. Although there are still years of intensive work ahead of us, the IKK/NF-κB pathway is a promising and important star on the intensive care horizon. Present address of Dr. Senftleben: Clinic of Anesthesiology, University of Ulm, Steinhövelstr. 9, 89075 Ulm, Germany. Address requests for reprints to: Michael Karin, PhD, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0636. E-mail: [email protected]
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