The fraktalkine receptor CX3CR1 is associated with progression of liver fibrosis in patients with chronic hepatitis C — David Scholten (2006) | RDL Network
The fraktalkine receptor CX3CR1 is associated with progression of liver fibrosis in patients with chronic hepatitis C
Article 2006 en
Authors
DS
David Scholten
ED
Edgar Dahl
TB
Thomas Berg
Abstract
1 min read
Aims: CX3CR1 constitutes the receptor for the chemokine fraktalkine (CX3CL1) which is involved in the recruitment of immune cells to the inflamed liver. In acute liver injury, CX3CR1 has been shown to be expressed on hepatocytes and bile ducts. Recently, two novel non-synonymous single nucleotide polymorphisms (SNPs) that affect the binding of fraktalkine have been identified in CX3CR1.
Federica Marchesi, Lorenzo Piemonti, Giuseppe Fedele, Annarita Destro, Massimo Roncalli, Luca Albarello, Claudio Doglioni, Achille Anselmo, Andrea Doni, Paolo Bianchi, Luigi Laghi, Alberto Malesci, Luigi Cervo, Maria Luisa Malosio, Michele Reni, Alessandro Zerbi, Valerio Di Carlo, Alberto Mantovani, Paola Allavena
Federica Marchesi, Lorenzo Piemonti, Giuseppe Fedele, Annarita Destro, Massimo Roncalli, Luca Albarello, Claudio Doglioni, Achille Anselmo, Andrea Doni, Paolo Bianchi, Luigi Laghi, Alberto Malesci, Luigi Cervo, Maria Luisa Malosio, Michele Reni, Alessandro Zerbi, Valerio Di Carlo, Alberto Mantovani, Paola Allavena
Discussion(0)
No comments yet. Be the first to comment.