The Cyclophilin Inhibitor Debio-025 is a Potent Inhibitor of Hepatitis C Virus Replication in vitro With a Unique Resistance Profile

Lotte Coelmont; Jan Paeshuyse; Suzanne J. F. Kaptein; Inge Vliegen; Ajay Kaul; De Clercq Erik; Brigitte Rosenwirth; Piétro Scalfaro; R. Crabbé; Ralf Bartenschlager

doi:10.1016/j.antiviral.2007.01.037

Related publications

Article2006

The cyclophilin inhibitor DEBIO-025 is a potent inhibitor of Hepatitis C virus replication in vitro

Lotte Coelmont, Jan Paeshuyse, Artur Kaul, Inge Vliegen, De Clercq Erik, Piétro Scalfaro, Brigitte Rosenwirth, R. Crabbé, JM Dumont, Ralf Bartenschlager, Johan Neyts

Article2006

The non‐immunosuppressive cyclosporin DEBIO‐025 is a potent inhibitor of hepatitis C virus replication in vitro†

Jan Paeshuyse, Artur Kaul, De Clercq Erik, Brigitte Rosenwirth, Jean‐Maurice Dumont, Piétro Scalfaro, Ralf Bartenschlager, Johan Neyts

Article2008

Inhibition of Human Immunodeficiency Virus Type 1 Replication in Human Cells by Debio-025, a Novel Cyclophilin Binding Agent

Roger G. Ptak, Philippe Gallay, Dirk Jochmans, Andrew P. Halestrap, Urs T. Rüegg, Luke A. Pallansch, Michael Bobardt, Marie‐Pierre de Béthune, Johan Neyts, De Clercq Erik, Jean‐Maurice Dumont, Piétro Scalfaro, Kamel Besseghir, Roland M. Wenger, Brigitte Rosenwirth

Article1989

Coumermycin A1 is a potent inhibitor of human immunodeficiency virus (HIV) replication in vitro

Masanori Baba, Rudi Pauwels, Jan Balzarini, Dominique Schols, De Clercq Erik

Article2007

GS-9190, a novel substituted imidazo-pyridine analogue, is a potent inhibitor of hepatitis C virus replication in vitro and remains active against known drug-resistant mutants

Inge Vliegen, Jan Paeshuyse, Eric Mabery, Betty Peng, I‐hung Shih, Laura S. Lehman, Hélène Dutartre, Barbara Selisko, Bruno Canard, Steven Bondy, Winston C. Tse, Hans Reiser, De Clercq Erik, William A. Lee, Gerhard Puerstinger, Weidong Zhong, Johan Neyts