The Breast Cancer Oncogene EMSY Represses Transcription of Antimetastatic microRNA miR-31
Article 2014 en
Authors
EV
Emmanuelle Viré
CC
Christina Curtis
VD
Verónica Dávalos
Abstract
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(Molecular Cell 53, 806–818; March 6, 2014) Due to an error during the submission of this manuscript, we inadvertently omitted the name of one of the authors, Isaia Barbieri, from the author list. The name now appears in the online version of the manuscript. The Breast Cancer Oncogene EMSY Represses Transcription of Antimetastatic microRNA miR-31Viré et al.Molecular CellFebruary 27, 2014In BriefEMSY gene amplification is an indicator of breast and ovarian cancers. Viré et al. report that EMSY is an oncogene that functions by repressing the transcription of antimetastatic miR-31. Repression involves the transcription factor ETS-1 and the histone demethylase KDM5B. miR-31 is a key player in cancer-related EMSY function because miR-31 expression reduces EMSY-mediated oncogenicity. Full-Text PDF Open Access
Emmanuelle Viré, Christina Curtis, Verónica Dávalos, Anna Git, Samuel C. Robson, Alberto Villanueva, August Vidal, Isaia Barbieri, Samuel Aparício, Manel Esteller, Carlos Caldas, Tony Kouzarides
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