The absolute configuration of 1-epialexine hemihydrate
Article 2008 en
Authors
AT
Amber L. Thompson
DW
D.J. Watkin
ZG
Zoltán A. Gál
Abstract
1 min read
The absolute and relative configurations of 1-epialexine are established by X-ray crystallographic analysis, giving (1S,2R,3R,7S,7aS)-1,2,7-trihydroxy-3-(hydroxymethyl)pyrrolizidine. The compound crystallizes as the hemihydrate C8H15NO4·0.5H2O, with hydrogen bonds holding the water molecule in a hydrophilic pocket between epialexine bilayers. In addition, a comparison was made between results obtained from examination of the Bijvoet pairs from data sets collected using molybdenum and copper radiation.
Laurence Jones, Jacqueline Hollinshead, George W. J. Fleet, Amber L. Thompson, D.J. Watkin, Zoltán A. Gál, Sarah F. Jenkinson, Atsushi Kato, Robert J. Nash
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