Systematic evaluation of the association between hemoglobin levels and metabolic profile implicates beneficial effects of hypoxia — Juha Auvinen (2021) | RDL Network
Systematic evaluation of the association between hemoglobin levels and metabolic profile implicates beneficial effects of hypoxia
Article 2021 en
Authors
JA
Juha Auvinen
JT
Joona Tapio
VK
Ville Karhunen
Abstract
1 min read
Activation of the hypoxia-inducible factor (HIF) pathway reprograms energy metabolism. Hemoglobin (Hb) is the main carrier of oxygen. Using its normal variation as a surrogate measure for hypoxia, we explored whether lower Hb levels could lead to healthier metabolic profiles in mice and humans (
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