Synthesis of Novel Carbocyclic Nucleosides with a Modified Cyclopentane Ring and Evaluation of Their Antiviral Activity

Isabel Nieto; M. José Figueira; JoséM. Blanco; Olga Caamaño; Franco Fernández; De Clercq Erik; Jan Balzarini

doi:10.1080/15257779908041525

Abstract

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New carbocyclic nucleosides with purine (compounds 2a-2c), 8-azapurine (compounds 2d and 2e) or pyrimidine (compound 3) as base were prepared and assayed for in vitro activity.

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