Synthesis and Screening for Anti-HIV Activity of Some N-Mannich Bases of Isatin Derivatives

S. N. Pandeya; Perumal Yogeeswari; Dharmarajan Sriram; De Clercq Erik; Christophe Pannecouque; Myriam Witvrouw

doi:10.1159/000007182

Back

Synthesis and Screening for Anti-HIV Activity of Some N-Mannich Bases of Isatin Derivatives

Article 1999 en

Abstract

1 min read

The effect of about 12 new compounds of Mannich bases of isatin against HIV-1 (IIIB) and HIV-2 (ROD) strains in MT 4 cells was studied. The screening method employed was MTT. In initial studies, one compound has shown maximum protection of 16% in subtoxic concentration.

Discussion(0)

No comments yet. Be the first to comment.

Related publications

Article1998

Anti-HIV Activity Of Some Mannich Bases Of Isatin Derivatives

eya, D. Sriram, De Clercq Erik, Christophe Pannecouque, Myriam Witvrouw

Article2001

Synthesis and anti-HIV activity of some isatin derivatives.

Sridhar Sk, Pandeya Sn, De Clercq Erik

Article1999

Synthesis, Antibacterial, Antifungal And Anti-HIV Activity Of Schiff And Mannich Bases Of Isatin With N-[6-Chlorobenzothiazol-2-yl] Thiosemicarbazide

eya, Dharmarajan Sriram, Gopal Nath, De Clercq Erik

Article2011

Synthesis, Antibacterial, Antifungal and Anti-HIV Evaluation of Schiff and Mannich Bases of Isatin and its Derivatives with Triazole

Surendra N. Pandeya, Dharmarajan Sriram, Gopal Nath, De Clercq Erik

Article2012

Synthesis, antiviral and cytotoxicity studies of novel N-substituted indophenazine derivatives

Parasuraman Selvam, DR Lakra, Christophe Pannecouque, De Clercq Erik