Synthesis and SAR of novel CXCR4 antagonists that are potent inhibitors of T tropic (X4) HIV-1 replication

Renato T. Skerlj; Gary Bridger; Ernest J. McEachern; Curtis Harwig; Christopher R. Smith; Trevor Wilson; D. R. VEALE; Helen S. Yee; Jason Crawford; Krystyna A. Skupinska; Rossana Wauthy; Wen Yang; Yongbao Zhu; David Bogucki; Maria Di Fluri; Jonathon Langille; Dana Huskens; De Clercq Erik; Dominique Schols

doi:10.1016/j.bmcl.2010.11.023

Related publications

Article2011

Design of novel CXCR4 antagonists that are potent inhibitors of T-tropic (X4) HIV-1 replication

Renato T. Skerlj, Gary Bridger, Ernest J. McEachern, Curtis Harwig, Christopher R. Smith, Alan Matthew Kaller, D. R. VEALE, Helen S. Yee, Krystyna A. Skupinska, Rossana Wauthy, Letian Wang, Ian R. Baird, Yongbao Zhu, Kate Burrage, Wen Yang, Michael Sartori, Dana Huskens, De Clercq Erik, Dominique Schols

Article2010

Discovery of Novel Small Molecule Orally Bioavailable C−X−C Chemokine Receptor 4 Antagonists That Are Potent Inhibitors of T-Tropic (X4) HIV-1 Replication

Renato T. Skerlj, Gary Bridger, Al Kaller, Ernest J. McEachern, Jason Crawford, Yuanxi Zhou, Bem Atsma, Jonathon Langille, Susan Nan, D. R. VEALE, Trevor Wilson, Curtis Harwig, Sigrid Hatse, Katrien Princen, De Clercq Erik, Dominique Schols

Article2009

Synthesis and SAR of novel CXCR4 antagonists that are potent inhibitors of T tropic (X4) HIV-1 replication

Discussion(0)

Related publications

Design of novel CXCR4 antagonists that are potent inhibitors of T-tropic (X4) HIV-1 replication

Discovery of Novel Small Molecule Orally Bioavailable C−X−C Chemokine Receptor 4 Antagonists That Are Potent Inhibitors of T-Tropic (X4) HIV-1 Replication

Design, Synthesis and SAR of New Potent HIV-1 RT Inhibitors

Inhibition of HIV Infection by Bicyclams, Highly Potent and Specific CXCR4 Antagonists

Reduced Fitness of HIV-1 Resistant to Cxcr4 Antagonists