SYNTHESIS ANDIN VITROANTIVIRAL ACTIVITY EVALUATION OF 9-(2-AZIDO-2,3-DIDEOXY-β-D-THREO-PENTOFURANOSYL)ADENINE DERIVATIVES

Satoshi Takamatsu; Kunisuke Izawa; Tokumi Maruyama; Satoshi Katayama; Naoko Hirose; De Clercq Erik

doi:10.1081/ncn-100002490

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SYNTHESIS ANDIN VITROANTIVIRAL ACTIVITY EVALUATION OF 9-(2-AZIDO-2,3-DIDEOXY-β-D-THREO-PENTOFURANOSYL)ADENINE DERIVATIVES

Article 2001 en

Abstract

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9-(2-Azido-2,3-dideoxy-beta-D-threo-pentofuranosyl)adenine derivatives (1a-e) containing a lipophilic function at the N-6 position in the purine ring were prepared and evaluated for their antiviral activity. The compounds 1a-e turned out to be inactive as antiviral agents.

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SYNTHESIS AND<i>IN VITRO</i>ANTIVIRAL ACTIVITY EVALUATION OF 9-(2-AZIDO-2,3-DIDEOXY-β-D-<i>THREO</i>-PENTOFURANOSYL)ADENINE DERIVATIVES

Abstract

Discussion(0)

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