Synthesis and cytotoxic evaluation of new terpenylpurines

Elena Valles Martín; Pablo A. García; José M. Miguel del Corral; Marta Pérez; Isabel Cristina Fernandes Rodrigues Ferreira; Ricardo C. Calhelha; Arturo San Feliciano; Ma Ángeles Castro

doi:10.1039/c6ra24254e

Abstract

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New 7/9-terpenylpurines were synthesized and evaluated as cytotoxics. Those derived from the natural compounds <italic>trans</italic>-communic and cupressic acids, showed GI<sub>50</sub> at the μM level.

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