Synthesis and Antitumor Properties of Some Neutral Triesters of 5-Fluoro-2'-deoxyuridine-5'-monophosphate and 3',5'-Cyclic Monophosphate

J. -L. Girardet; Gilles Gosselin; Christian Périgaud; Jan Balzarini; De Clercq Erik; J.‐L. IMBACH

doi:10.1080/15257779508012442

Back

Synthesis and Antitumor Properties of Some Neutral Triesters of 5-Fluoro-2'-deoxyuridine-5'-monophosphate and 3',5'-Cyclic Monophosphate

Article 1995 en

Abstract

1 min read

Abstract Several new prodrugs of 5-fluoro-2′-deoxyuridine 5′-monophosphate and 3′,5′-cyclic monophosphate were synthesized and their antitumor activities were evaluated in vitro.

Discussion(0)

No comments yet. Be the first to comment.

Related publications

Article1986

Synthesis and antitumor and antiviral properties of 5-halo- and 5-(trifluoromethyl)-2'-deoxyuridine 3',5'-cyclic monophosphates and neutral triesters

J. Béres, Gyula Sági, Wesley G. Bentrude, Jan Balzarini, De Clercq Erik, László Ötvös

Article1986

Synthesis and antitumor and antiviral properties of 5-alkyl-2'-deoxyuridines 3',5'-cyclic monophosphates, and neutral cyclic triesters

J. Béres, Wesley G. Bentrude, Jan Balzarini, De Clercq Erik, László Ötvös

Article1989

Synthesis and cystostatic and antiviral activities of 1-.beta.-D-ribofuranosyl-5-alkylcytosine (5-alkylcytidine) cyclic 3',5'-monophosphates

J. Béres, Wesley G. Bentrude, László Ötvös, Jan Balzarini, De Clercq Erik

Article1986

ChemInform Abstract: Synthesis and Antitumor and Antiviral Properties of 5‐Alkyl‐2′‐deoxyuridines, 3′,5′‐Cyclic Monophosphates, and Neutral Cyclic Triesters.

J. Béres, Wesley G. Bentrude, Jan Balzarini, De Clercq Erik, L. OETVOES

Article1989

2'-Fluorinated isonucleosides. 1. Synthesis and biological activity of some methyl 2'-deoxy-2'-fluoro-2'-pyrimidinyl-D-arabinopyranosides

M. Bobek, Sungwhan An, D. Skrincosky, De Clercq Erik, Ralph J. Bernacki