Suzuki cross-coupling of benzo[b]thiophene 2-and 3-boronic acids with 3-bromo-2-((Z)-2-bromovinyl)thiophene

Isabel Cristina Fernandes Rodrigues Ferreira; Jens Schlegel; Maria João R.P. Queiroz; Gerhard Maas

Suzuki cross-coupling of benzo[b]thiophene 2-and 3-boronic acids with 3-bromo-2-((Z)-2-bromovinyl)thiophene

Article 2001 en

Abstract

1 min read

ln order to obtain precursors for a ring C convergent method to thienodibenzothiophene by an intramolecular Heck reaction, 3-bromo-2-((Z)-2-bromovinyl)thiophene 1 was prepared from 3-bromothiophene by ortho-directed lithiation followed by electrophilic formylation and formation of the bromovinyl moiet via the dibromo compound.

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