Supplementary Tables 1 - 7 from BRAF Inhibitor Resistance Mechanisms in Metastatic Melanoma: Spectrum and Clinical Impact

<p>PDF file - 197KB, Table S1 Exome sequencing data summary. Table S2 Candidate resistant variants identified in Prog melanomas. Table S3 Median MAPK activity scores of Pre-treatment versus Prog melanoma metastases and associated P-value. Table S4 Gene Set Enrichment Analysis of MAPK-inhibited Prog tumors (n=6) vs. MAPK-re-activated Prog tumors (n=15). Table S5 Inter-tumoral heterogeneity of BRAF inhibitor resistance mechanisms and MAPK activity. Table S6 BRAF inhibitor resistance mechanism and response to subsequent MAPK inhibitors. Table S7 Amplification and Sequencing Primers.</p>