Sulfadoxine-pyrimethamine for uncomplicated falciparum malaria: Sulfadoxine-pyrimethamine is not working in Malawi — Sir Nicholas White (2004) | RDL Network
EDITOR—The paper by Plowe et al entitled “Sustained clinical efficacy of sulfadoxine-pyrimethamine for uncomplicated falciparum malaria” might be better titled “Sustained lack of efficacy of sulfadoxine-pyrimethamine….”1 By the start of the study period five years ago, molecular genotyping showed that Plasmodium falciparum in Malawi had already acquired significant resistance to the combination.1 2 This explains the sustained lack of efficacy; …
Craig Bonnington, Anthony Nuwa, Katherine Theiss-Nyland, Richard Kajubi, Moses R. Kamya, Joaniter I. Nankabirwa, Chris Ebong, Jane Nabakooza, Jimmy Opigo, David Salandini, O.I Musa, Chayanin Sararat, James A Watson, Kanokon Suwannasin, Stéphane Proux, Urairat Koesukwiwat, Joel Tärning, Mallika Imwong, James Tibenderana, François Nosten, Sir Nicholas White
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