Successful treatment of severe recalcitrant psoriasis with combination infliximab and methotrexate

Brian Kirby; Alexander Marsland; A.J. Carmichael; Christopher Em Griffiths

doi:10.1046/j.1365-2230.2001.00753.x

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Successful treatment of severe recalcitrant psoriasis with combination infliximab and methotrexate

Article 2001 en

Abstract

1 min read

Plaques of psoriasis contain increased levels of cytokines, including tumour necrosis factor-alpha (TNF-alpha), which are thought to be essential to the maintenance of the psoriatic process. We report the successful treatment of severe, recalcitrant psoriasis when infliximab (a monoclonal antibody to TNF-alpha) was used in combination with methotrexate.

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