Abstract Stroke prevention is one of the cornerstones of management in patients with atrial fibrillation (AF). As part of the ABC (Atrial fibrillation Better Care) pathway (A: Avoid stroke/Anticoagulation; B: Better symptom control; C: Cardiovascular risk and comorbidity optimisation), stroke risk assessment and appropriate thromboprophylaxis is emphasised. Various guidelines have addressed stroke prevention. In this review, we compared the 2017 APHRS, 2018 ACCP, 2019 ACC/AHA/HRS, and 2020 ESC AF guidelines regarding the stroke/bleeding risk assessment and recommendations about the use of OAC. We also aimed to highlight some unique points for each of those guidelines. All four guidelines recommend the use of the CHA2DS2-VASc score for stroke risk assessment, and OAC (preferably NOACs in all NOAC-eligible patients) is recommended for AF patients with a CHA2DS2-VASc score ≥2 (males) or ≥3 (females). Guidelines also emphasize the importance of stroke risk reassessments at periodic intervals (e.g. 4–6 months) to inform treatment decisions (e.g. initiation of OAC in patients no longer at low risk of stroke) and address potentially modifiable bleeding risk factors.
Tatjana Potpara, Gheorghe‐Andrei Dan, Elina Trendafilova, Artan Goda, Zumreta Kušljugić, Šime Manola, Ljilja Musić, R. Musetescu, Elisabeta Bădilă, Gorana Mitić, Vilma Paparisto, Elena Dimitrova, Marija Polovina, Stanislav L Petranov, Hortensia Djergo, Daniela Lončar, Amira Bijedić, Sandro Brusich, Professor Gregory Lip, Tatjana Potpara, Marija Polovina, Srdjan Milanov, Marija Pavlović, Tijana Petrović, Stefan Simović, M Milanov, J Savić, Sanja Gnip, Pavica Radović, Snežana Marković, I. Koncarevic, Jelena Gavrilović, T. Acimovic, D Djikic, Semir Malić, Jusuf Hodzic, Milovan Stojanović, M. Deljanin Ilic, M. Zlatar, Dragan Matić, S. Lazić, Vladan Perić, Sanja Marković, Snezana Kovacević, Aleksandra Arandjelovic, Milika Ašanin, Marija Zdravković, Gheorghe‐Andrei Dan, Anca Breha, Anca Rodica Dan, R. Musetescu, Mircea Ioachim Popescu, Elisabeta Bădilă, Cătălina Arsenescu Georgescu, Sorina Pop, Raluca Popescu, S Neamţu, Floriana Oancea, Elina Trendafilova, Elena Dimitrova, Evgenii Goshev, Anna Velichkova, Stanislav L Petranov, Delyana Kamenova, Penka Kamenova, Svetoslava Elefterova, Valentin Shterev, Maria Zekova, Stela Diukiandzhieva, Borislav Dimitrov, Tihomir Sotirov, Valentina Simeonova, Dimitrina Drianovska, Liliya Ivanova Vasileva Boiadzhieva, Darina Buchukova, Artan Goda, Hortensia Gjergo, Alma Mijo, E Shirka, Viktor Gjini, U Ekmekçiu, Ina Refatllari, Daniela Lončar, Denis Mršić, Hazim Tulumovic, Belma Pojskić, Alma Sijamija, Indira Karamujic, Irma Bijedić, Sanela Halilovic, Šime Manola, Ivan Zeljković, Nikola Pavlović, Vjekoslav Radeljić
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