The results of this study suggest that stressful life events are significantly more likely to occur in depressed children, particularly females, compared to anxious children, and that these events are predominantly characterized by independent events outside of the child's control. The results also suggest that loss events may be specific for depression in children. Interestingly, stress does not appear to impact the HPA axis in children, which is true for anxious, depressed, and normal control children. The temporal occurrence and severity, as well as the type of stressful life events as they relate to the onset and maintenance of anxiety and depression in children, need to be more fully explored.
Kristy Benoit Allen, Jennifer S. Silk, Suzanne Meller, Patricia Z. Tan, Cecile D. Ladouceur, Lisa Sheeber, Erika E. Forbes, Ronald E Dahl, Greg J. Siegle, Dana L. McMakin, Neal D. Ryan
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