Strategies to Design and Analyze Targeted Sequencing Data

Honghuang Lin; Min Wang; Jennifer A. Brody; Joshua C. Bis; Josée Dupuis; Thomas Lumley; Barbara McKnight; Kenneth Rice; Colleen M. Sitlani; Jeffrey G. Reid; Jan Bressler; Xiaoming Liu; Brian C. Davis; Andrew D. Johnson; Christopher J. O’Donnell; Christie Kovar; Huyen Dinh; Yuanqing Wu; Irene Newsham; Han Chen; Andi Broka; Anita L. DeStefano; Mayetri Gupta; Kathryn L. Lunetta; Yongmei Liu; Charles C. White; Chuanhua Xing; Yanhua Zhou; Emelia Benjamin; Renate B. Schnabel; Susan R. Heckbert; Bruce M. Psaty; Donna M. Muzny; L. Adrienne Cupples; Alanna C. Morrison; Eric Boerwinkle

doi:10.1161/circgenetics.113.000350

Related publications

Article2015

Abstract 18374: Targeted Sequencing and Massively Parallel Reporter Assay Identify the Functional Variation Underlying the 4q25 Locus for Atrial Fibrillation

Nathan R. Tucker, Jiangchuan Ye, Honghuang Lin, Michael A McLellan, Emelia Benjamin, Kathryn L. Lunetta, Tarjei S. Mikkelsen, Steven A. Lubitz, Patrick T. Ellinor

Article2022

Contribution of Rare and Low-Frequency Variants to Multiple Sclerosis Susceptibility in the Italian Continental Population

Ferdinando Clarelli, Nadia Barizzone, Eleonora Mangano, Miriam Zuccalà, Chiara Basagni, Santosh Anand, Melissa Sorosina, Elisabetta Mascia, Silvia Santoro, Franca Rosa Guerini, Eleonora Virgilio, Antonio Gallo, Alessandro Pizzino, Cristoforo Comi, Vittorio Martinelli, Gıancarlo Comı, Gianluca De Bellis, Maurizio Leone, Massimo Filippi, Federica Esposito, Roberta Bordoni, Filippo Martinelli Boneschi, Sandra D’Alfonso

Article2022

Genetic analysis of over half a million people characterises C-reactive protein loci

Saredo Said, Raha Pazoki, Ville Karhunen, Urmo Võsa, Symen Ligthart, Barbara Bodinier, Fotios Koskeridis, Paul Welsh, Behrooz Z. Alizadeh, Daniel I. Chasman, Naveed Sattar, Marc Chadeau‐Hyam, Εvangelos Εvangelou, Paul M Ridker, Paul Elliott, Ioanna Tzoulaki, Abbas Dehghan

Article2017

New Blood Pressure–Associated Loci Identified in Meta-Analyses of 475 000 Individuals

Aldi T. Kraja, James P. Cook, Helen R. Warren, Praveen Surendran, Chunyu Liu, Εvangelos Εvangelou, Alisa K. Manning, Niels Grarup, Fotios Drenos, Xueling Sim, Albert V. Smith, Najaf Amin, Alexandra I. F. Blakemore, Jette Bork‐Jensen, Ivan Brandslund, Aliki‐Eleni Farmaki, Cristiano Fava, Teresa Ferreira, Karl‐Heinz Herzig, Ayush Giri, Franco Giulianini, Megan L. Grove, Xiuqing Guo, Sarah E. Harris, Henri Theil,

Article2023

Antithrombin, Protein C, and Protein S: Genome and Transcriptome-Wide Association Studies Identify 7 Novel Loci Regulating Plasma Levels

Yuekai Ji, Gerard Temprano‐Sagrera, Lori A. Holle, Allison Bebo, Jennifer A. Brody, Ngoc‐Quynh Le, Kadri Kangro, Michael R. Brown, Ángel Martínez-Pérez, Colleen M. Sitlani, Pierre Suchon, Marcus E. Kleber, David Emmert, Ayse Bilge Ozel, Dre’Von A. Dobson, Weihong Tang, Dolors Llobet, Russell P. Tracy, Jean‐François Deleuze, Graciela E. Delgado, Martin Gögele, Kerri L. Wiggins, Juan Carlos Souto,