Specific nucleic acid detection based on fluorescent light-up probe from fluorogens with aggregation-induced emission characteristics

Yuqiong Li; Ryan T. K. Kwok; Ben Zhong Tang; Bin Liu

doi:10.1039/c3ra41983e

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Specific nucleic acid detection based on fluorescent light-up probe from fluorogens with aggregation-induced emission characteristics

Article 2013 en

Abstract

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We report a new fluorescent light-up probe design strategy by conjugating fluorogens with aggregation-induced emission (AIE) characteristics, e.g. tetraphenylethene with a single-stranded oligonucleotide for homogeneous specific complementary DNA detection in solution.

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