Significant association of PD-L1 expression with human papillomavirus positivity and its prognostic impact in oropharyngeal cancer

Angela Hong; Peter M. Ferguson; Tristan Dodds; D. Brian Jones; Mengbo Li; Jean Yang; Richard A Scolyer

doi:10.1016/j.oraloncology.2019.03.012

Abstract

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Our findings suggested that different immune profiles in oropharyngeal cancer by HPV status and the effect of HPV on the outcomes is modified by PD-L1 expression.

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Significant association of PD-L1 expression with human papillomavirus positivity and its prognostic impact in oropharyngeal cancer

Abstract

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Related publications

PD-L1 expression in tonsillar cancer is associated with human papillomavirus positivity and improved survival: implications for anti-PD1 clinical trials

Pyruvate Kinase M2 Is Required for the Expression of the Immune Checkpoint PD-L1 in Immune Cells and Tumors

PD-L1 Negative Status is Associated with Lower Mutation Burden, Differential Expression of Immune-Related Genes, and Worse Survival in Stage III Melanoma

Data from PD-L1 Negative Status is Associated with Lower Mutation Burden, Differential Expression of Immune-Related Genes, and Worse Survival in Stage III Melanoma

Data from PD-L1 Negative Status is Associated with Lower Mutation Burden, Differential Expression of Immune-Related Genes, and Worse Survival in Stage III Melanoma