Sex-Specific Early Retinal Dysfunction in Mutant TDP-43 Transgenic Mice

Ju Gao; Henri Leinonen; Evan J. Wang; Mao Ding; George Perry; Krzysztof Palczewski; Xinglong Wang

doi:10.3233/jad-231102

Abstract

1 min read

Together our findings suggest a sex-specific vulnerability within the retina in the early disease stage, and highlight the importance of retinal changes and mitochondrial markers as potential early diagnostic indicators for ALS, FTD, and other TDP-43 related neurodegenerative conditions.

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