Sex-Specific Associations of Cardiovascular Risk Factors and Biomarkers With Incident Heart Failure

Navin Suthahar; Emily S. Lau; Michael J. Blaha; Samantha M. Paniagua; Martin G. Larson; Bruce M. Psaty; Emelia Benjamin; Matthew Allison; Traci M. Bartz; James L. Januzzi; Daniel Levy; Laura M.G. Meems; Stephan J. L. Bakker; João A.C. Lima; Mary Cushman; Douglas S. Lee; Thomas J. Wang; Christopher R. deFilippi; David M. Herrington; Matthew Nayor; Ramachandran S. Vasan; Julius M. Gardin; Jorge R. Kizer; Alain G. Bertoni; Norrina B. Allen; Ron T. Gansevoort; Sanjiv J. Shah; John S. Gottdiener; Jennifer E. Ho; Rudolf A. de Boer

doi:10.1016/j.jacc.2020.07.044

Abstract

1 min read

CV risk factors are strongly and similarly associated with incident HF in both sexes, highlighting the similar importance of risk factor control in reducing HF risk in the community. There are subtle sex-related differences in the predictive value of individual biomarkers, but the overall improvement in HF risk estimation when included in a clinical HF risk prediction model is limited in both sexes.

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Sex-Specific Associations of Cardiovascular Risk Factors and Biomarkers With Incident Heart Failure