Sex Differences in Platelet Toll-Like Receptors and Their Association With Cardiovascular Risk Factors

Milka Koupenova; Eric Mick; Ekaterina Mikhalev; Emelia Benjamin; Kahraman Tanrıverdi; Jane E. Freedman

doi:10.1161/atvbaha.114.304954

Abstract

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We report the first study to demonstrate that platelets express all TLR transcripts using a large community-based observational cohort. These transcripts are more abundant in women and have distinct associations with cardiovascular risk and inflammatory biomarkers that vary by sex.

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