Sex- and Age-Related Differences in the Management and Outcomes of Chronic Heart Failure: An Analysis of Patients from the ESC HFA EORP Heart Failure Long-Term Registry

There was a decline in GDMT use with advanced age in both sexes. Sex was not an independent predictor of GDMT or adverse outcomes. However, age >75 years independently predicted lower GDMT use and higher all-cause mortality in patients with LVEF ≤45%.