Sequential Open-Label Study of the Safety, Tolerability, and Pharmacokinetic Interactions between Dihydroartemisinin-Piperaquine and Mefloquine in Healthy Thai Adults — Borimas Hanboonkunupakarn (2019) | RDL Network
Sequential Open-Label Study of the Safety, Tolerability, and Pharmacokinetic Interactions between Dihydroartemisinin-Piperaquine and Mefloquine in Healthy Thai Adults
Antimicrobial Agents and Chemotherapy 63(8)
Article 2019 English
Authors
BH
Borimas Hanboonkunupakarn
RP
Rob W. van der Pluijm
RH
Richard M. Hoglund
Abstract
1 min read
Artemisinin-based combination therapies (ACTs) have contributed substantially to the global decline in Plasmodium falciparum morbidity and mortality, but resistance to artemisinins and their partner drugs is increasing in Southeast Asia, threatening malaria control. New antimalarial compounds will not be generally available soon.
Achaporn Yipsirimetee, Phornpimon Tipthara, Borimas Hanboonkunupakarn, Rupam Tripura, Dysoley Lek, Krittikorn Kümpornsin, Lee M, Jetsumon Sattabongkot, Arjen M. Dondorp, Sir Nicholas White, Kevin C. Kobylinski, Joel Tärning, Kesinee Chotivanich
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