Many biomarkers have been evaluated for use in sepsis. Most of the biomarkers had been tested clinically, primarily as prognostic markers in sepsis; relatively few have been used for diagnosis. None has sufficient specificity or sensitivity to be routinely employed in clinical practice. PCT and CRP have been most widely used, but even these have limited ability to distinguish sepsis from other inflammatory conditions or to predict outcome.
Omar S. M. El Nahhas, Chiara Maria Lavinia Loeffler, Zunamys I. Carrero, Marko van Treeck, Fiona R. Kolbinger, Katherine Hewitt, Hannah S. Muti, Mara Graziani, Qinghe Zeng, Julien Caldéraro, Nadina Ortiz‐Brüchle, Tanwei Yuan, Michael Hoffmeister, Hermann Brenner, Alexander Brobeil, Jorge S. Reis‐Filho, Jakob Nikolas Kather
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