Sensitivity–Specificity of Tau and Amyloid β Positron Emission Tomography in Frontotemporal Lobar Degeneration

Alma Ghirelli; Nirubol Tosakulwong; Stephen D. Weigand; Heather M. Clark; Farwa Ali; Hugo Botha; Joseph R. Duffy; Rene L. Utianski; Marina Buciuc; Melissa E. Murray; Sydney A. Labuzan; Anthony J. Spychalla; Nha Trang Thu Pham; Christopher G. Schwarz; Matthew L. Senjem; Mary M. Machulda; Matthew Baker; Rosa Rademakers; Massimo Filippi; Clifford R. Jack; Val J. Lowe; Joseph E. Parisi; Dennis W. Dickson; Keith A. Josephs; Jennifer L. Whitwell

doi:10.1002/ana.25893

Abstract

1 min read

Molecular PET shows expected correlations with Alzheimer-related pathology but lacks sensitivity to detect mild Alzheimer pathology in FTLD. Regional flortaucipir uptake was able to separate CBD and PSP. ANN NEUROL 2020;88:1009-1022.

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