The results of this analysis indicate that recently duplicated paralogs evolve faster than orthologs with the same level of divergence and similar functions, but apparently do not experience a phase of neutral evolution. We hypothesize that gene duplications that persist in an evolving lineage are beneficial from the time of their origin, due primarily to a protein dosage effect in response to variable environmental conditions; duplications are likely to give rise to new functions at a later phase of their evolution once a higher level of divergence is reached.
Jean-François Goût, Parul Johri, Olivier Arnaiz, Thomas G. Doak, Simran Bhullar, Arnaud Couloux, Frédéric Guèrin, Sophie Malinsky, Linda Sperling, Karine Labadie, Éric Meyer, Sandra Duharcourt, Michael E Lynch
Jean-François Goût, Yue Hao, Parul Johri, Olivier Arnaiz, Thomas G. Doak, Simran Bhullar, Arnaud Couloux, Frédéric Guèrin, Sophie Malinsky, А. А. Потехин, Natalia Sawka‐Gądek, Linda Sperling, Karine Labadie, Éric Meyer, Sandra Duharcourt, Michael E Lynch
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