Role of mitochondrial dysfunction in Alzheimer's disease
Article 2002 en
Authors
RC
Rudy J. Castellani
KH
Keisuke Hirai
GA
Gjumrakch Aliev
Abstract
1 min read
Abnormalities in mitochondrial function relate to the spectrum of pathological changes seen in Alzheimer's disease. Here we review the causes and consequences of mitochondrial disturbances in Alzheimer's disease as well as how this information might impact on therapeutic approaches to this disease.
Keisuke Hirai, Gjumrakch Aliev, Akihiko Nunomura, Hisashi Fujioka, Robert L. Russell, Craig Atwood, Toby Johnson, Yvonne Kress, Harry V. Vinters, Massimo Tabaton, Shun Shimohama, Ayla Cash, Sandra L. Siedlak, Peggy L.R. Harris, Paul K. Jones, Robert B. Petersen, George Perry, Mark A. Smith
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