Ring transformation of an isoxazoline-1-oxide. A novel transformation product, dimethyl 7-chloro-3a,4-dihydro-5aH-benzofuro(3,3a-d)isoxazole-3,4-dicarboxylate.

Shonosuke Zen; Kiyobumi Takahashi; Eisuke Kaji; Hikaru Nakamura; Yöichi Iitaka

doi:10.1248/cpb.31.1814

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Hikaru Nakamura

Nagoya University

Ring transformation of an isoxazoline-1-oxide. A novel transformation product, dimethyl 7-chloro-3a,4-dihydro-5aH-benzofuro(3,3a-d)isoxazole-3,4-dicarboxylate.

Article 1983 en

Authors

SZ
Shonosuke Zen
KT
Kiyobumi Takahashi
EK
Eisuke Kaji

Abstract

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4-p-Chlorophenyl-3, 5-bis (methoxycarbonyl) isoxazoline-1-oxide reacted with excess titanium tetrachloride in dichloromethane to yield a novel fused heterocycle, dimethyl 7-chloro-3a, 4-dihydro-5aH-benzofuro-[3, 3a-d] isoxazole-3, 4-dicarboxylate in good yield. The result of this structural determination by single crystal X-ray analysis is reported.

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Ring transformation of an isoxazoline-1-oxide. A novel transformation product, dimethyl 7-chloro-3a,4-dihydro-5aH-benzofuro(3,3a-d)isoxazole-3,4-dicarboxylate.

Abstract

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