Revisiting the diagnosis of ‘resistant hypertension’: what should we do nowadays’

Hypertension is one of the leading causes of death globally Despite the widespread use of antihypertensive drugs and treatment strategies, many patients with hypertension fail to achieve target blood pressure (BP) control, a condition called resistant hypertension (RH). RH is a major clinical problem as it is associated with a high risk of hypertension-mediated organ damage (HMOD), including chronic kidney disease (CKD), and premature cardiovascular diseases (CVD) Therefore, early identification and effective management strategies have the potential to improve hypertension treatment and lower cardiovascular morbidity and mortality of the hypertensives population, especially RH.