RESOLUTION, ABSOLUTE CONFIGURATION, AND PHOTORACEMIZATION OF CHIRAL TROPONOID ACETALS, CYCLOHEPTA[2,1-b:2,3-b′]DI[1,4]BENZOXAZINES

Yoshio Okamoto; Shiro Honda; Heimei Yuki; Hikaru Nakamura; Yöichi Iitaka; Tetsuo Nozoe

doi:10.1246/cl.1984.1149

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RESOLUTION, ABSOLUTE CONFIGURATION, AND PHOTORACEMIZATION OF CHIRAL TROPONOID ACETALS, CYCLOHEPTA[2,1-b:2,3-b′]DI[1,4]BENZOXAZINES

Article 1984 en

Abstract

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Abstract The title chiral troponoid compounds were resolved in optically pure forms by high-performance liquid chromatography on a chiral poly(triphenylmethyl methacrylate) column. The compounds showed large optical rotations. The absolute configuration of (−)-3,12-dichloro derivative was found to be R by X-ray analysis. Resolved enantiomers were racemized upon UV irradiation in solution.

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