Research Paper - ANTIBACTERIAL, ANTI-INFLAMMATORY AND DIURETIC EFFECT OF FLAVONOIDS FROM MARCHANTIA CONVOLUTA

Dried leaves of Marchantia convoluta are largely used to
\nprotect livers, and to treat tumefaction of skins in China. Flavonoids
\nfrom Marchantia convoluta (MCF) were the active components against
\nhepatitis B virus. In this study, the pharmacological properties of MCF
\nconsisting of flavonoids determined by HPLC were examined in
\nparticular. High dosage of MCF (20 and 40 μg/mL) could
\nsignificantly reduce the activity of ALT and AST in the serum of mice
\nwith acute hepatic injury caused by CCl4 and increase the contents of
\nTP and ALP. MCF could inhibit the auricle tympanites of mice caused by
\ndimethylbenzene. MCF inhibited obviously colibacillus, tyhoid bacillus,
\nStaphylococcus aureus , bacillus enteritidis, hemolytic
\nstreptococci type B and Diplococcus pneumoniae . The results
\nshowed that MCF possess distinct effect of antibiosis,
\nanti-inflammation and diuresis in mice.