Reproducibility of the whole-brain N-acetylaspartate level across institutions, MR scanners, and field strengths.

Béatrice Benedetti; D.J. Rigotti; S. Liu; Massimo Filippi; Robert I. Grossman; Oded Gonen

Abstract

1 min read

Absolute quantification against a standard makes the WBNAA concentration insensitive to the MR hardware used to acquire it. This important attribute renders it a robust surrogate marker for multicenter neurologic trials.

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