Replication Data for: Improving statistical power in severe malaria genetic association studies by augmenting phenotypic precision — James A Watson | RDL Network
Replication Data for: Improving statistical power in severe malaria genetic association studies by augmenting phenotypic precision
Dataset en
Authors
JW
James A Watson
KM
Kathryn Maitland
TW
Thomas N. Williams
Abstract
1 min read
This is a replication dataset for the manuscript titled: "Improving statistical power in severe malaria genetic association studies by augmenting phenotypic precision." This dataset contains complete blood count data (platelet counts and total white blood cell counts) for severely ill patients enrolled in either studies of severe malaria or general severe febrile illness in Africa and Asia. For reproducibility of analyses we also provide parasite densities; hospital outcome; sickle trait status for the Kenyan children; plasma PfHRP2 for FEAST and Bangladesh adults; age. Variable Description: study: Vietnam (2 randomized trials in severe malaria: Hien et al; Phu et al); Bangladesh/Thailand (observational studies in severe malaria); FEAST (Maitland et); Kenya (KEMRI severe malaria cohort) platelets: number of platelets x1000 per uL of blood wbc: number of white blood cells x1000 per uL of blood pfhrp2: PfHRP2 concentration in plasma (ng/mL) age: years HbAS: sickle trait genotype (0: not sickle trait; 1: sickle trait) outcome: in hospital survival (0: survived; 1: died) parasitaemia: parasite density per uL of blood. The package presented contains data and replication code. The code is also available on github repo: code is on this github repo: https://github.com/jwatowatson/Kenyan_phenotypic_accuracy
James A Watson, Carolyne Ndila, Sophie Uyoga, Alexander W. Macharia, Gideon Nyutu, Shebe Mohammed, Caroline Ngetsa, Neema Mturi, Norbert Peshu, Benjamin Tsofa, Kirk A. Rockett, Stije J. Leopold, Hugh Kingston, Elizabeth C. George, Kathryn Maitland, Nicholas Day, Arjen M. Dondorp, Philip Bejon, Thomas N. Williams, Chris Holmes, Sir Nicholas White
James A Watson, Carolyne Ndila, Sophie Uyoga, Alexander W. Macharia, Gideon Nyutu, Shebe Mohammed, Caroline Ngetsa, Neema Mturi, Norbert Peshu, Benjamin Tsofa, Kirk A. Rockett, Stije J. Leopold, Hugh Kingston, Elizabeth C. George, Kathryn Maitland, Nicholas Day, Arjen M. Dondorp, Philip Bejon, Thomas N. Williams, Chris Holmes, Sir Nicholas White
James A Watson, Carolyne Ndila, Sophie Uyoga, Alexander W. Macharia, Gideon Nyutu, Shebe Mohammed, Caroline Ngetsa, Neema Mturi, Norbert Peshu, Benjamin Tsofa, Kirk A. Rockett, Stije J. Leopold, Hugh Kingston, Elizabeth C. George, Kathryn Maitland, Nicholas Day, Arjen M. Dondorp, Philip Bejon, Thomas N. Williams, Chris Holmes, Sir Nicholas White
James A Watson, Sophie Uyoga, Perpetual Wanjiku, Johnstone Makale, Gideon Nyutu, Neema Mturi, Elizabeth C. George, Charles J. Woodrow, Nicholas Day, Philip Bejon, Robert O. Opoka, Arjen M. Dondorp, Chandy C. John, Kathryn Maitland, Thomas N. Williams, Sir Nicholas White
Sophie Uyoga, James A Watson, Perpetual Wanjiku, J. C. Rop, Johnstone Makale, Alexander W. Macharia, Silvia N. Kariuki, Gideon Nyutu, Shebe Mohammed, Moses Mosobo, Neema Mturi, Kirk A. Rockett, Charles J. Woodrow, Arjen M. Dondorp, Kathryn Maitland, Sir Nicholas White, Thomas N. Williams
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