Relations Between Aortic Stiffness and Left Ventricular Mechanical Function in the Community

Vanessa Bell; Elizabeth L. McCabe; Martin G. Larson; Jian Rong; Allison A. Merz; Ewa Osypiuk; Birgitta T. Lehman; Plamen Stantchev; Jayashri Aragam; Emelia Benjamin; Naomi M. Hamburg; Ramachandran S. Vasan; Gary F. Mitchell; Susan Cheng

doi:10.1161/jaha.116.004903

Abstract

1 min read

Multiple measures of increased aortic stiffness were cross-sectionally associated with worse GLS after adjusting for hemodynamic variables. Parallel reductions in left ventricular long axis shortening and proximal aortic longitudinal strain in individuals with a stiffened proximal aorta, from direct mechanical ventricular-vascular coupling, offers an alternative explanation for the observed relations.

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