Relation between MR abnormalities and patterns of cognitive impairment in multiple sclerosis

Marco Rovaris; Massimo Filippi; Monica Falautano; L. Minicucci; Maria A. Rocca; Vittorio Martinelli; Giancarlo Comi

doi:10.1212/wnl.50.6.1601

Abstract

1 min read

Lesion loads on PD-weighted MRI and MTI-derived measures are associated with cognitive decline in MS patients. Overall macroscopic and microscopic brain damage is more important than the corresponding regional brain disease in determining deficits of selective cognitive domains.

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