Real-time monitoring of the mitophagy process by a photostable fluorescent mitochondrion-specific bioprobe with AIE characteristics — Weijie Zhang (2015) | RDL Network
Real-time monitoring of the mitophagy process by a photostable fluorescent mitochondrion-specific bioprobe with AIE characteristics
Article 2015 en
Authors
WZ
Weijie Zhang
RK
Ryan T. K. Kwok
YC
Yilong Chen
Abstract
1 min read
An isothiocyanate-functionalized tetraphenylethene is synthesized and used as a fluorescent bioprobe for mitochondrion imaging with high specificity and photostability. The covalent conjugation of the bioprobe to mitochondrial proteins endows it with high resistance to microenvironmental changes, enabling it for real-time monitoring of mitophagy.
Bo Situ, Sijie Chen, Engui Zhao, Chris Wai Tung Leung, Yilong Chen, Yuning Hong, Jacky W. Y. Lam, Zilong Wen, Wei Liu, Wenqing Zhang, Lei Zheng, Ben Zhong Tang
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