Quantification of chloride in sweat by using ion chromatography instead of chloridometer

Abstract This study reports about a new ion chromatography method for the detection of chloride ions in sweat as an alternative to the gold standard of the chloridometer. Information about necessary materials, required preparations, reference ranges, advantages and disadvantages of this method is provided. We finally demonstrate that this method is useful to screen for cystic fibrosis in sweat samples. Article Highlights. A new ion chromatography method for detection of chloride ions in sweat is described References ranges for this method are given Advantages and disadvantages are discussed The usefulness of this method is shown in 145 sweat samples